Researchers have discovered that tofacitinib, a drug normally used to treat rheumatoid arthritis, could restore pigmentation in people with vitiligo. Autoimmunity is thought to play a role in its pathogenesis. The white spots typically begin around the ends of fingers- I thought my nail polish remover was removing the color of my skin around the nailbed, white areas around mouth, and near outer corners of eyes. Why is vitiligo considered an autoimmune disease?
In a study appearing in the March 22 New England Journal of Medicine, scientists supported by the National Institutes of Health’ s National Institute of Arthritis and Musculoskeletal and Skin Diseases ( NIAMS) have discovered a connection between a specific gene and the inflammatory skin condition vitiligo, as well as a possible host of autoimmune diseases. Vitiligo, with an estimated prevalence ranging from 0. I was diagnosed with vitiligo a couple years ago.
Jun 24, · So, they reasoned that the JAK inhibitor tofacitinib ( Xeljanz) - - currently approved to treat rheumatoid arthritis- - might also help ease vitiligo. Vitiligo und arthritis. 5% to 1%, is characterized by selective loss of melanocytes and patchy depigmentation of the skin and mucous membranes. Vitiligo is thought to have a genetic linkage but little is known about the association with rheumatoid arthritis ( RA), an inflammatory type of arthritis that is often diagnosed in young adults ( mostly women).